ToxRe’s scientific risk professionals are offering the following
of published and non-published proprietary safety/toxicity data concerning:
* new substances
(and related Brands®) to
be launched in the near future,
* new substances (and related Brands®) recently launched,
* generic substances (and related Brands®) to be relaunched
for new applications, * interactions among pharmaceutical substances
(and related Brands®),
* interactions between food/drinks and drug substances (and related
on toxicological matters
ToxRe’s experienced team of scientists and insurance/financial
specialists is offering manufacturers and financial carriers the unique
opportunity to obtain an independent and objective "second
opinion" on the tolerance of their (new) commercial substances
by making intelligent use of available toxicological information.
and registration assistance for companies
seeking governmental sales approvals for their (new) substances and/or
formulations (and related Brands®).
A reliable “second opinion” on the safety
and tolerance of a new chemical substance (supported by relevant production,
formulation, application and marketing data) may result in a successful
re-assessment of the manufacturer’s future potential liability
exposure prior to the launch of (a) new chemical, pesticidal or
of the potential liability exposure for companies created by the re/launch
of generic and/or new substances (and related Brands®).
by scientific transparency
A reliable scientific re-assessment of a manufacturer’s potential
liability exposure (expressed in monetary terms) also represents a reliable
basis on which to create innovative technical and financial solutions
acceptable and beneficial to the manufacturer and the investors concerned.
Cooperation with ToxRe provides manufacturers and investors a unique
opportunity to obtain an objective insight into the sustainability of
Critical and hazardous substances
ToxRe is regularly updating a list of critical and hazardous substances
such as pesticides, pharmaceuticals, chemicals and biochemicals, etc.
found on exclusion lists distributed by re/insurers in various international
markets. All shown
substances are believed to have caused serious adverse effects to humans
and/or to the environment. The purpose of drawing up this list is not
only to provide the name of the active substance - as distinct for one
or another commercial synonym - but also to provide some guidance as
to the nature of the observed adverse effects as well as to the actual
proprietary status for each indicated individual substance. On specific
request by manufacturers selective parts of our basic updated "ToxRe-List"
can be made available to manufacturing clients for explanatory purposes.
ToxRe attaches the greatest importance to ensuring that intellectual
property rights and exclusivity rights of proprietary toxicological
and safety data are safeguarded. ToxRe ise aware that such protection
is crucial for the success of the chemical and pharmaceutical industry.
ToxRe does guarantee confidential handling of such intellectual property
as part of its consultancy service.
ToxRe treats all submitted proprietary toxicity data as well as its
subsequent toxicological findings, liability assessments and insurance
solutions as strictly confidential. None of the end-point assessments
and second opinion reports compiled by ToxRe concerning proprietary
substances is published without the written agreement of the clients/owners.
Unless otherwise agreed, ToxRe reports are forwarded to clients in encrypted
electronic form or via registered private post.
The team of ToxRe:
and liability exposure specialist:
-Gijs van den Hurk (B.Sc. Tropical Agriculture, Toxicology.
Senior risk engineer for toxicology and liability exposure. Specialized
in crop protection chemicals, pesticides, agrochemicals, pharmaceuticals,
nutraceuticals, hormones, food additives, fine & bulk chemicals,
polymers, contaminants, asbestos, man-made mineral fibres, etc.
- Matthias Refardt (Agricultural Ing. CV*).
Specialised in crop protection chemicals, pesticides, biopesticides,
biotechnical products, fertilizers, etc.).
- Gerhard Nohynek
(Ph.D. Toxicology. CV*).
Diplomat of the American Board of Toxicology, EUROTOX registered toxicologist.
Specialized in drug toxicology, cosmetics, pesticides, biochemicals,
pharmaceuticals, nutraceuticals, food additives, etc.).
- Gyselle van
den Hurk-Strub (Dr. med. vet. CV*).
Preferences: veterinary pharmaceuticals, diagnostic imaging (roentgenology,
sonography) and surgery. E-mail:
van den Hurk-Schmidlin (lic. phil. clinical psychology FSP.
Preferences: clinical psychology, neuropsychology, behavioral medicine,
& management assistance:
Roger Dekkers (Student in Business Administration,
Erasmus University, Rotterdam. CV*)
CV* . . . . . . . . .Detailed CV available on request.